People Don’t Like You? Blame Your Genes

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Do people tend to like you?

Do you believe you are a kind, empathetic person? Your genes may be able to tell you the honest answer. In facts, there is a gene that is so influential in our socio-emotional sensitivity, that in one research, people were able to observe and  accurately judge whether a complete stranger had the “empathy” gene in under 20 seconds.  Multiple studies have proven that we are genetically predisposed to how kind we are.

Empathy and kindness lies in our genes. Oxytocin, dubbed “the cuddle chemical” or “love hormone” is a hormone associated with trust and is necessary for forging intimate relationships with loved ones. The OXTR gene, or the oxytocin receptor gene has three variants- A and G and AG and each are strongly correlated with a certain social behavior.

You are one of three types of people: GG, AG, or AA

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The GG Variant People

  • Predisposed for empathy and kindness
  •  Displays altruistic and charitable behavior
  •  Greater ability to cope with stress [PMID 19934046]
  •  Greater parenting skills and maternal sensitivity to children [PMID 19015103]
  •  Reduced risk for social anxiety and autism [PMID 20724662]
  •  Better social and communication skills; more likeable by strangers at first impression
  •  Optimistic
  • Displays more pro-social behavior
  •  Less lonely [PMID 19376182]
  • Better able to discern the emotional state of others [PMID 19934046]

 

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The AG or AA Variant People

  • Less pro-social physical and verbal cues that display empathy
  •  increased risk for impaired social interaction & communication [PMID 20724662]
  •  Twice as less likely to be charitable and altruistic, especially under stress or fear
  •  Less trusting
  •  Does not handle stress well
  •  Less maternal sensitivity and parenting ability [PMID 19015103]
  •  Feels more lonely and more emotionally co-dependent on others  [PMID 19376182]
  • Higher risk for social anxiety

 

However, social behavior is influenced by other genetic factors and many non genetic factors as well, such as culture, environment, and childhood experiences. Even though this genetic marker is strongly associated with socio-emotional sensitivity and well-being, this does not mean you absolutely have the associated social behavior. However, it is interesting to note all the different research that manifested from this gene.

The Significance of this Gene

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Oxytocin is both a hormone and a neurotransmitter that influences social and emotional processing throughout our body. It is dubbed the “cuddle hormone” because it is released when two people deeply bond. OXTR is an oxytocin receptor gene that has two variants- G and A- that is associated with  empathy and stress reactivity. Due to genetic variation, people can be either GG, AA or AG. Compared with people with the homozygous GG allele, people with AG or AA allele showed far less empathy and higher stress reactivity. Injections of oxytocin increased prosocial behaviors, generosity, feelings of trust and empathy in humans. If this OXTR gene is completely knocked out (eliminated) in lab animals, they display aberrant social behavior, increased aggression and offspring neglect.

 

  • Even slight genetic variation can quickly be noticed by others- even complete strangers. In one research, strangers watched a 20 second silent recording of 23 couples interacting with each other and judged how trustworthy and likeable someone seemed based on prosocial traits. In the 10 least trusted people, 9 had at least one copy of the A genotype.

 

  • Mice that has the OXTR receptor gene completely knocked out showed aggressive and aberrant behavior and even refused to acknowledge it’s own offspring.

 

  •  Those with at least one copy of the A genotype is more likely to have an autism diagnosis.

 

  •  Study examining the relationship between 176 mothers and their children showed that mothers with the GG genotype has a significantly more sensitive parenting style than those with AG or AA genotypes. [PMID 19015103]
Personalized Wine

Wineapp_ImgEver have a mild panic attack when you’re presented with a mammoth selection of wine? If you are not a wine connoisseur, you probably had an instance or two when you looked up reviews online or sheepishly asked your server for a recommendation. But crowd-sourcing wine ratings is like asking a stranger what type of music or art you’d like. It’s a complex beverage with thousands of different kinds, and individual preference vary with culture, geography, personality, and genetics. That’s right. Genetics. Wine preferences among people vary vastly based on their unique genetic makeup. The same wine can very much taste differently depending on which version of gene they have.


Wine Characteristics

There are over thousands of different types and flavors, but all wine can be described with 5 basic taste characteristics listed below:

  1. Sweetness: Or “dryness,” this is the sweet sensation due to the sugar content in the wine. This can be the sweetness of the fruit, the actual sugar content, or the alcohol itself since alcohol is a sweet liquid.
  2. Acidity: The sour, tart, or zesty flavor in a food or beverage. As grapes ripen the amount of acidity goes down. The acidity of wine feels tart, fresh, and tingly.
  3. Tannin: The source of bitterness in wine. This flavor comes from the phenolic compounds in the skin and seeds of grapes and tend to have a drying feeling in your mouth.
  4. Fruit: A distinguishing feature of wine is the main fruit or floral flavor.
  5. Body: The viscosity, or the weight, of the wine, which is affected by alcohol content. Light bodied wines are usually more watery, thin, and have lower alcohol content.  Medium to full-bodied wines are thicker, more rich in flavor, and usually have higher alcohol content.

Understanding these 5 tastes allows you to fine tune your sensory abilities and find favorites easily. It allows you to categorize, distinguish and recognize wine tastes. However, even if you don’t speak ‘sommelier’, your genes got you covered when it comes to finding the best drink for you.

Can your DNA determine your wine preference?

Taste preferences are partly genetically determined. While most of us can taste and experience those 5 characteristics, the degree of liking for those tastes inherently varies individually. Luckily, there are known genetic markers that measure preference for each of those tastes. Your DNA will let you know exactly what type and characteristic of wine your taste buds prefer. With this information, you will never have to guess your favorites or play Russian roulette with wine ever again.